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ETORICOXIB

Etoricoxib

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2). This reduces the generation of prostaglandins (PGs) from arachidonic acid.

IUPACName
5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]- 2,3'-bipyridine
CASNumber
202409-33-4
MolecularFormula
C18H15CIN2O2S
Synonyms
Algix;Etoxib;Etocox;MK 663;Tauxib;Etobrix;Arcoxia;Kingcox;MK 0663;Etropain
Application
For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
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