Methotrexate
Methotrexate
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate dehydrogenase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
- IUPACName
- (2S)-2-[(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)amino]pentanedioic acid
- CASNumber
- 59-05-2
- MolecularFormula
- C20H22N8O5
- Synonyms
- METHOTREXATE;METHYLAMINOPTERIN;METHYLAMINOPTERINE;ANTIFOLAN;L-(+)-AMETHOPTERIN;4-AMINO-N 10-METHYLPTEROYL-L-GLUTAMIC ACID;4-AMINO-10-METHYLPTEROYLGLUTAMIC ACID;(+)-4-AMINO-10-METHYLFOLIC ACID
- Application
- A deuterated folic acid antagonist
